Acetyl Hexapeptide-3 (Topical)

Description

Acetyl Hexapeptide-3 200mg (Topical Peptide)

This product is intended for research purposes only. To be used by trained professionals only.

Acetyl Hexapeptide-3, also known as Argireline, is a synthetic anti-wrinkle cosmetic peptide that has gained significant attention within the skincare industry for its potential anti-aging properties. This peptide is a fragment of SNAP-25, a substrate of Botulinum toxin, and is designed to mimic the effects of Botox when applied topically, offering a non-invasive alternative to injectable treatments. It functions by inhibiting the release of neurotransmitters, particularly acetylcholine, which plays a key role in muscle contraction. By limiting facial muscle contractions, Acetyl Hexapeptide-3 is believed to reduce the appearance of fine lines and wrinkles, particularly around the eyes, forehead, and mouth [1].

Acetyl Hexapeptide-3, is widely studied for its potential to diminish wrinkle formation in skin tissues, presenting a less invasive option compared to bacterial toxins. By permeating the skin layers, it specifically targets the muscle cells just beneath the surface.

Developed to act as a competitive inhibitor of SNAP-25 (synaptosome-associated protein 25 kDa), Acetyl Hexapeptide-3 is believed to obstruct the assembly of the SNARE complex. By simulating the N-terminal end of SNAP-25, it purportedly impedes the exocytosis of neurotransmitters.

Research suggests that Acetyl Hexapeptide-3 can effectively address dynamic wrinkles resulting from repetitive facial expressions like smiling or frowning. Moreover, it has been suggested that this peptide could contribute to the prevention of wrinkle formation, making it an appealing ingredient for individuals seeking to maintain youthful skin [2]. Its mechanism of action aligns with the growing trend of consumers seeking non-surgical solutions for addressing signs of aging.

Additionally, Acetyl Hexapeptide-3 has been integrated into a range of anti-aging topical formulations designed to enhance skin appearance. While there is a notable interest in its potential benefits, it’s worth noting that additional basic studies are needed to comprehensively understand its effects on skin mechanical properties and long-term efficacy. As the demand for non-invasive anti-aging solutions continues to rise, Acetyl Hexapeptide-3 stands as a promising peptide in the scientific research of cosmeceuticals, offering a targeted approach to addressing the visible signs of aging without resorting to invasive procedures.

While further research is warranted, Acetyl Hexapeptide-3 holds potential as a valuable component in anti-aging skincare formulations, catering to individuals looking for innovative and non-invasive approaches to maintaining youthful and radiant skin.

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References:

[1] Acetyl hexapeptide-3 in a cosmetic formulation acts on skin mechanical properties – Clinical study, December 2015Brazilian Journal of Pharmaceutical Sciences 51(4):901-909 by Kassandra Azevedo Tadini, Daiane G Mercurio and Patricia Campos.

[2] Double-blind, Randomized Trial on the Effectiveness of Acetylhexapeptide-3 Cream and Palmitoyl Pentapeptide-4 Cream for Crow’s Feet. J Clin Aesthet Dermatol. 2023 Feb;16(2):37-43. by Aruan RR, Hutabarat H, Widodo AA, Firdiyono MTCC, Wirawanty C, Fransiska L.

Molecular formula: C34H60N14O12S

Molecular weight: 889.0 g/mol

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DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://m.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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