B7-33

Description

B7-33 Peptide Vial 

This product is intended for research purposes only. To be used by trained professionals only.

B7-33 is a synthetic peptide derived from human relaxin-2, which is a hormone that plays a role in the regulation of several physiological processes, including vascular function, inflammation, and tissue repair. B7-33 has been shown to replicate the vasoprotective functions of human relaxin-2, and has been found to have therapeutic potential in several disease states.

Research has shown that B7 33 can promote tissue repair and reduce fibrotic encapsulation. One study found that coatings containing B7-33 were able to reduce fibrotic encapsulation in implantable devices, suggesting that the peptide may have potential in improving the biocompatibility of such devices [1]. Additionally, B7 33 has been shown to prevent the development of endothelial dysfunction, indicating its potential in the treatment of cardiovascular diseases.

Furthermore, B7-33  peptide has been shown to attenuate adverse cardiac remodelling after myocardial infarction (MI) in mice. A study found that long-term administration of B7 33 led to improved cardiac function and decreased fibrosis in mice with MI, suggesting that the peptide may have therapeutic potential in the treatment of heart disease [2].

Studies have also explored the potential of B7 33 in inhibiting pancreatic cancer liver metastasis. A lipidated derivative of B7-33 was found to prolong the half-life of the peptide in vivo and improve its efficacy in inhibiting cancer cell migration and invasion. This suggests that B7-33 may have potential therapeutic uses in cancer treatment [3].

Overall, B7-33 has shown promising results in promoting tissue repair, reducing fibrosis and inflammation, and improving cardiovascular health. However, further research is needed to fully understand the mechanisms of action and potential applications of this peptide.

References:

[1] https://pubmed.ncbi.nlm.nih.gov/ 31713411/

[2] https://www.ahajournals.org/ doi/10.1161/JAHA.119.0157 48

[3] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC7674520/

Sequence: VIKLSGRELVRAQIAISGMSTWS KRSL

Storage: Lyophilized peptides stored below -18°C.

Research use only. Not for human or animal consumption!

ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.

DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://m.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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