£27.94 – £50.88
Buy Kisspeptin Nasal Spray
Kisspeptin is a naturally occurring peptide hormone that plays a pivotal role in human reproduction by stimulating the release of gonadotropin-releasing hormone (GnRH). It’s considered an essential gatekeeper of sexual maturation, as its deficiency can lead to delayed or absent puberty. Ongoing research suggests potential applications of Kisspeptin in treating reproductive health issues like infertility and polycystic ovary syndrome.
Kisspeptin 15ml contains: 5mg
Kisspeptin 30ml contains: 10mg
435 in stock
This product is intended for research purposes only. To be used by trained professionals only.
Kisspeptin, encoded by the KISS1 gene, is a crucial peptide hormone that plays a significant role in human reproduction. It acts as a potent stimulator of gonadotropin-releasing hormone (GnRH), thereby influencing the release of luteinising hormone and follicle-stimulating hormone, which are critical for sexual maturation and function [1].
Kisspeptin operates through its receptor, GPR54, and has been found to have essential roles in the neuroendocrine regulation of reproduction. Deficiencies or mutations in either Kisspeptin or GPR54 can lead to pubertal failure and infertility, underscoring their importance in reproductive health [2].
Additionally, Kisspeptin neurons exhibit distinct patterns of activity that are synchronized with the circadian rhythm, suggesting a role in the timing of the preovulatory LH surge. This indicates that Kisspeptin nasal spray might play a part in generating the LH surge through activation of GnRH neurons [3].
The Kisspeptin neural network’s anatomy is complex and widespread in mammals, with various distribution patterns across species. This network’s structural and functional multiplicity has been demonstrated even in lower vertebrates and fish, indicating its evolutionary conservation [4].
Interestingly, environmental factors can control the production and action of Kisspeptin, implying a role in seasonal reproduction. Changes in Kisspeptin peptide responses to peripheral injections have been observed in response to different environmental stimuli [5]. Research has also shown that Kisspeptin signalling can be synchronized and excited by high-frequency stimulation, highlighting its potential role in modulating reproductive rhythms. This finding opens up new avenues for understanding how Kisspeptin nasal spray can regulate the reproductive system at the cellular and network levels.
[1] https://www.sciencedirect.com/ science/article/abs/pii/S00068993 10019992
[2] https://academic.oup.com/humupd/ article/12/5/631/778116
[3] https://onlinelibrary.wiley.com/ doi/abs/10.1111/j.1365-2826.2011. 02162.x
[4] https://academic.oup.com/bio lreprod/article/79/4/776/2557727
[5] https://academic.oup.com/endo/ article/148/3/1158/2501844
Purity: >98%
Molecular Formula: C63H83N17O14
Molecular Weight: 1302.462 g/mol
Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH
ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.
DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://m.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.
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